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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '354d4358e9d7618adfd30bbb879647835684fff298a165d5c77d30662fcf0038' 
  AND token = '/l3XDDmjfLOi1hEHegBDfMVE5nXWsL77ch8sDPtcXfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}