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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '050745918e1aec3fa9744497c6ae570a228400d90b9e0d030b6691f4bec0e9e5' 
  AND token = 'FQ+3zBvag/nA+SrZ0HzhpiC3MIX9NNdZkqmq59Edzik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}