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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b6648b59a0a5b4ddfce5f5b37c3b9135be19b67f158ebdda7da9cf07b12b04e' 
  AND token = 'B01zk+DFNaOa76X1zNTxdedxI0PFXMOgWJfds3Tmvb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}