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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd27b680f16dcdd581225f8f1c630ba4e9484b999297afa572d3fac2a26caf108' 
  AND token = 'O9xkkWyLtIa5ZPCAYpA5R39i3p6yrlw/l4GdT0JVb0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}