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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0582250f6c538e2535aec7ffe2f97c5e4816a680e4c9f33b4381008b47e665e' 
  AND token = 'diEDivw2h4FEtToc+/yXKn8SlKuaIVZWatdg759SvjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}