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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '193d8cf3b7240c9e319c6da9ab1e53d7278e749cf3b3bdbfb80c385f622a5a78' 
  AND token = 'o4Sm5j3ZrQtMkw110qNy6H6ahs3P4RCl8PwYscRmt2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}