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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb4d82dcc42ed5d6598a801591ad5758aa5643e2e98ea622035c697d0b31fc17' 
  AND token = 'bH6Y3OOSNq6MCuzdUK05AnE30+9WHOnTNN3tMzHsbB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}