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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '338e85e322ddf2be3e0381a1460e9ed228efd30108ce7af3ae8a871cbcc3c089' 
  AND token = 'hQ9OI2sBm+QUb62GUlFEEqi7zAzGemv4KisiGmLSgk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}