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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50b722da31dee04cb4a6190f47e9cde39265af75b8c4c19dbdb61ad65f8901d9' 
  AND token = 'TsKqPh3IpbGw2X1rIRO62g9mXRXnsiWZi4RrKdX5mls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}