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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1eeac7f81bc22a1e76c19d25521382a0436dd5753f8b631456057918ba06cc04' 
  AND token = '/uLi+V1qm6uqwf4bCGoEeLLbaMyCMWs4LL5p/iW18Do=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}