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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1beef95bc7ba5ef10d58d89e99f476ab65d5c5f5054eaee637ac5aba6f1045f8' 
  AND token = 'Xx+NAlpOTfLzPmIYjnK/rrp8tQfIFPjpzqejUsPv5sw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}