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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66f0c312ae78a7ddd3fc7880327f51c4128e8f9167737a1e7b23328a6be370da' 
  AND token = 'GDF1pSPth81R54Yr9UG7Z8+ggEWMYzHYJUpStZ5XfmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}