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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac19d649d7b3c787f4990d0a1dd09078deeb20c2a3c50b437e17b233bd53f05a' 
  AND token = 'd41A6Rpwk/EkJMOPtrJx+AMdncxtUIru0IZfi5mUon4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}