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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '500f07b7977d923be8cfe3abfb67c17a0badb43a73a1e8b110aec5bd046fc05a' 
  AND token = 'r64NvAGhoS5OUh1+yEdJQCCI5xcu1BvEYLEdRGCyvt0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}