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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ef23308b5e32d4c0b5e3f73fff527bb1c0bee6c12d404338d333dc9de8cc058' 
  AND token = '+HIPp9f9wBScCIVq/j5EeKSOZiEDfP8F7hfDXnNibuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}