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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b334c6429e118fc9b51de8bc08669071f36c3a94dd9f13eeac34627680a713b7' 
  AND token = 'JKtuC2KupRel8CXzUg5sFDLIuMzPCsWTz0DX5ogTQBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}