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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '341252bbb3d9d8109120f0aefa70bad0211bf9c3bdb8833f04d98f2dcd569757' 
  AND token = 'XVoTgokNl6dALnMqqgLBVZdC1KjLBBmt7gA5qbP6fxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}