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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29b515611bbb6306e5896ca6b8b15f7104ece72d2e843a97b72c01d0a4e16d64' 
  AND token = 'QxaXWaAvrmeNMOOzorA59IDrobGRN5ISDyd9Vta+pgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}