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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b82c6fd9120470e6f75f43dd5dbe21a83953b231746b7099a27dc481093ceb2' 
  AND token = 'IeKksg9UQKAuIZkH63T2VINDaffds6INZPfeu3cExts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}