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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec78540fc4919be69d5b7d1747c51758495445f19a5de3644dcd463d377df4d4' 
  AND token = 'jM0t10obQRyGTrPLZKZLcG8LqJIK2pQyS16fM9cBV8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}