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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95b5cb75719949c4b8ef24cf11321ab28c54a52304df3726a4958a30dd7d8c53' 
  AND token = 'E1JlbceUCeqXWZ0mNUKWLoo08pRLDn/OB4ryGMMEiLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}