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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed0a3adc634e038cff7a29124b8755d71972b3a174f234d186da52fb93447082' 
  AND token = 'xpBFAwpWGpveL7Em13An80A4uhKlBzxtWZ2m3GNoU00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}