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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89b295d3bf9b77ffdc17053c7efea769443334cbf54dc14e262d98f7d3b2b6bd' 
  AND token = 'TAzY4TDP2JBhSt8o6MePeNrtG5OC2bSTTinCtUKrcdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}