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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a5c678900cd16c948b072c8ee39c97b59c0cb108f17abe3648ada2b2a52848b' 
  AND token = 'ZiHWJ1H6N1QCQbYbGX9dyAwA2VrYjx3H1wCFKnbi7r0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}