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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2fd8d3f7d9dcfbb78972f94b4310bebdd794cd8567cf66e63f6749e98fa8182' 
  AND token = 'fRDOjBZA+MuU6XIQGPMmjp5mxXpX8hl1IFyakdQvXro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}