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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0e77190052e056bf8728c63794bfca41f6d29b6c14ba24cccb819bf993cee53' 
  AND token = 'uHT9iOEeoAz/q0I18x95tjNyhX1uSk9zp/Jn1y3IwCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}