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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66fe3e03b0e9ec771e2c831ec70a3cd72009f6c6f18be66d3bfb98b1bd36717d' 
  AND token = '8IMy/u3GYbG9Qu47ySPaa0hk3Vd/XojkLd6iYiOkCuE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}