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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8262fe75be7e7cdb2c09e6fb0ebc132d1461cba6b7ed67f631f2a2b59e5faeb6' 
  AND token = 'Uvo0VDkyEQuZKmBVCsZBHvEicZzNnOLfymVUDoIjRg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}