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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5a4cfad49c464a302b19ea866c42532595523f79171720c014e8400e7c4226b' 
  AND token = 'krQmKjdvKN3scXEd27CO+tQW3alYf2zjtTcS5e+5g2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}