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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17028ac354e12934c65114a6d3278dba737c0f0af3005c9ffcfbcb0d57054e5a' 
  AND token = 'JTWl7SVCMULz/ir4pD/ImqwBlDEiZ4uBV0jQT3lf8bI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}