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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8223f7940e07e0ca011a7c2216a3cfaea46123deedca6892024313eca0d4995e' 
  AND token = 'cwG2oTNtIr55Y5kmuabKGbqqjG8CLIDQ3JLR3sQHqC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}