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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c28716c8d5dc8beb1f7b003f167aecb6964748d5d37467d6267ce6583b57ef9f' 
  AND token = '8D21GgbNGhS82R1hMuQAK18LmCPhGLFDREv3FtR23Ag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}