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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a5c2bbe24e86e25aa1bc62e35244404cb22e1cac2e15c7716d1686364f85206' 
  AND token = '/baknvRbWh3l9uJgdFWEMicGdnZXMyiLmJVImXy7vzM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}