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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c94a6228eaf222cdecc7f94ec1c82e19249af54a871a7f97c4316e2e5d45b97e' 
  AND token = 'eGbpLxPz6RL8QkxA2U2IYMNrTYC+wUE+xPHjJ/tAN4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}