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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4550fbc25b36d165271c94cf0c86c60d1dbf77146409889246d04a59ee0e735' 
  AND token = 'lU7YrSgwrRANUmILw3aGEW25SNB1ECdzCnPczP70oAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}