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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21c842998f52ac6328f3a6c9ae1cc39a1c46b3b393ec956d6b0febb451e66da5' 
  AND token = '2nfY20UmfLvekFmBCSAxYUySQQf4wS4E6vFxlR9jpyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}