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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66eb275333b41f3e22aa31f265320ba34c9bccba23a35567e6d8dfa339f7d480' 
  AND token = 'qPPIISd6c5TGkbkFRlOPza48Zyf5tKMV+J8pW6LSqes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}