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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f50c9cf1dd833addae1b4bd947e72dbf649b05afb12e7838de2e657b42d05b5' 
  AND token = 'FfOL1YqKfYAN47VTnMnHv7W5WCBijX8k1c9rXGrwY6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}