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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45fd24588b53ffbeb614b939f60391ddf57c7ab7c30eaf8b1debdeeeaa652403' 
  AND token = '0LFs2P962WBk91I5UIU6mYY8NgwDrPcwVFbx/OjD4Ms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}