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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52a26dc49280174ccbf524c5bc9db9c432025edd85a418da77185afb8300ec43' 
  AND token = 'X+8n5B5NeAmH9l+sHpMmjPW+IeJEB/KAHhGX28hZxMg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}