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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e04474385a6b10169ede728dc453cb4eb69f7b1377faa46f5a6c78c0890cdc7' 
  AND token = '/aN7cSzjVDhTzkDvWxSvJW92zyQuj4kqQ5vSTY/a4RQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}