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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af55fdd0412d93e86d22ba017115a24e438386037d253d5a634e32acfad9e370' 
  AND token = 'UHnxc7vVluXyo+2FzPi3Km5QqNyIrOpmh3f1uveTLVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}