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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '740bf731bf2ca2b1750d12787787e1916c39721ac52cd73011b4661104a6013e' 
  AND token = 'kcOu9xsh7FbV5jQwO/zhBkCa3WyLwfbIbPj0wpwsZSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}