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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1aeb7f6c59c34b1535ca3b1b88b352b4b7f34b71edd5bdf3d578cc49fbf92e46' 
  AND token = 'Dr0CxiFougrEG4Gbth2xuWGzCOlMrVOGFlt7+i5qKfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}