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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '729249a85db399014ecb7b8425304a6f699d8dad99e42f85b40082242e230156' 
  AND token = 'uOfSFNk+7+FlIV4aFTrh5xi46e3PcALgMY48/CaJBgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}