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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cd07ea8dd8055c79d16142d9447c069986fe9d33b34e0eeeb8e46daa89465a5' 
  AND token = 'FSuroUaprGi9b2CkJ9Cp0snZja6zTri5CAeNFPPfWqY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}