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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6500fa6b8065cb1fdc2d18ccef41b39e3e08819d7c5511c0596fca8b9b216903' 
  AND token = '2mbJjkO34AvhiqAyHS+vYNw+wVBkAiTWI9xGAS6OBUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}