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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f3f4865450b9ef801b70635bf94d2e98d96d437ec6019a3f525a1c4fb5f64b3' 
  AND token = 'LtW493ytVKEI1TnMeYOomamh713VpCZEe/Y0Izjfqhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}