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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd253aab76690e2fb0c2b1505b96b6f7b2e14125af10251cde0daad548b1b712b' 
  AND token = '/PZRzbc43YEAme4dBIGf8mstSxbMEJal5uCyB9cfNSc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}