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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ebe9c27873cf2872a13c154eca814669707a24e2af230b49afbf8c0447886b76' 
  AND token = 'VBCUa8lXjXyVpDD4RrUnBNYYWMcfgSGxvYIGdyOzVxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}